Supply Chain Redefined

The MainStem Supply Chain Ecosystem is the ONLY fully integrated B2B procurement software built to solve complex issues for the cannabis industry.

We give cannabis operators and suppliers the tools and data to manage their business – all in one place.

Buy, Sell and Grow...
at the speed of cannabis

Whether you are a cannabis operator or a supplier, our cannabis-specific software platform is designed with your unique supply chain challenges in mind.

The MainStem Procurement Platform allows you to source and sell everything cannabis companies need to run their businesses.

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Empowering Cannabis Operators
Our August supply savings through MainStem paid for our yearly subscription"
Laura Clauser
Procurement Manager, Ethos Cannabis
45% Cost Savings
Digitizing your procurement processes not only simplifies your business, it can significantly reduce your operational costs.
Learn How

The MainStem Network Effect

We are the only enterprise-level supply chain solution that connects cannabis buyers and an extensive network of suppliers within an integrated friction-free commerce platform.

This network is what makes us different from traditional procurement software solutions and allows us to bring additional value to the industry. Built by experts in cannabis supply and distribution, our ecosystem provides the tools, services and partnerships for both operators and suppliers to grow their business.

A Streamlined Procure-to-pay Software for cannabis operators

MainStem is an unparalleled Procurement Platform that connects buyers with a network of suppliers to provide holistic, data-driven spend management and control at a regional, national, and global level.

MainStem provides a sourcing and purchasing software solution custom-tailored to the workflows and regulations of the cannabis industry. From a single location to MSO, we have solutions to fit all your procurement needs.

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Suppliers: Join our Network and Grow your Supply Business

Expand your market share. Enter new territories. And build out your footprint with MainStem, the cannabis industry’s intelligent supply chain solution. As one of our in-network suppliers, you can sell, fulfill, negotiate, consolidate, and streamline ... all at the speed of cannabis.

With 3,000+ cannabis B2B users registered on our Procurement Platform you can immediately expand your customer base through MainStem. With our tools and API integration, you can easily list your products on our platform using your existing ecommerce software. Our platform allows you to consolidate your orders while gaining valuable data insights.

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Selling made Simple
We love the platform and the ability to track orders, look at past orders, top products, etc. is very easy."
- Sierra Bags
2,200 Locations
Gain immediate access to thousands of new cannabis customers with multiple locations across the United States.
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Experience white glove customer service

For us, customer support is more than just answering a phone.

When you choose MainStem, you are partnering with a team of experts in the cannabis industry, with years of experience in cannabis software, supply sourcing, procurement technology, industry regulations and customer relationships.

Your onboarding and dedicated customer advocacy team will customize a plan to get your team up and running on the platform with no stress on your end.

Our team of sourcing and product specialists are here to help you every step of the way - from basic ancillary supply purchasing to complex custom packaging projects.

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Connect your Tech

Built with open API, the MainStem Procurement Platform integrates with your existing software investments, including ERP and accounting solutions, back-office tools, cannabis software and ecommerce services.

Our integrations help automate many of your workflows, saving you time and money on manual processes. By working seamlessly with your current tech stack, MainStem consolidates your day-to-day business into a user-friendly platform,  giving you full visibility across your whole operation with a single log-in.

Connecting your systems together under Mainstem allows you to holistically manage your spend, processes and leverage your data insights to grow your business.

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Make Data-Driven Decisions

Whether you are a cannabis operator or a supplier, insights into your purchasing and sales activity helps you forecast, budget, manage inventory and plan for the future. The MainStem Procurement Platform brings all your data into a single place for full visibility and accountability.

Accolades and Recognition

1 in 10

Licensed US cannabis companies have placed orders through MainStem


Products have been shipped through our platform


Products available on MainStem


Year-over-year growth


Vendors listed on our platform
MainStem Platform
The MainStem Supply Chain Ecosystem is the ONLY fully integrated B2B procurement software built to solve complex issues for the cannabis industry.We give cannabis operators and suppliers the tools and data to manage their business – all in one place.
Stay connected to MainStem.
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